| 贵州白香猪apoA5基因多态性初步分析 |
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| 引用本文： | 杨远青,刘若余. 贵州白香猪apoA5基因多态性初步分析[J]. 黑龙江畜牧兽医, 2011, 0(15) |
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| 作者姓名： | 杨远青 刘若余 |
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| 作者单位： | 贵州大学动物科学学院贵州省动物遗传育种与繁殖重点实验室; |
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| 基金项目： | 贵州省农业科技攻关项目(黔科合NY字[2009]3073) |
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| 摘 要： | 贵州白香猪为贵州特有的地方品种,为了研究贵州白香猪apoA5基因多态性,试验采用直接测序法对贵州白香猪apoA5基因全序列2 473 bp进行单核苷酸多态性(SNPs)检测。结果表明:在apoA5基因的内含子2和外显子3中分别检测出1个、11个变异位点;有4个突变发生在氨基酸编码区内,其中3个突变为同义突变,而G1 185A突变为非同义突变,导致了密码子由CGC突变为CAC,从而导致氨基酸由精氨酸(Arg)突变为组氨酸(His);另外7个突变位点发生在3'-UTR;在检测出的12个变异位点中,G1 690C及G1 821C突变符合Hardy-Weinberg平衡状态,其余10个位点偏离了Hardy-Weinberg平衡。
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| 关 键 词： | 贵州白香猪 apoA5基因 多态性 |
Primary analysis on polymorphism of apoA5 gene of Guizhou White xiang pig |
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| YANG Yuan-qing,LIU Ruo-yu. Primary analysis on polymorphism of apoA5 gene of Guizhou White xiang pig[J]. Heilongjiang Animal Science And veterinary Medicine, 2011, 0(15) |
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| Authors: | YANG Yuan-qing LIU Ruo-yu |
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| Affiliation: | YANG Yuan-qing,LIU Ruo-yu(College of Animal Sciences,Guizhou University,Guizhou Key Lab of Animal Genetics Breeding and Reproduction,Guiyang 550025,China) |
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| Abstract: | Guizhou White xiang pig is a specific breed pig in Guizhou province.To study and research the apoA5 gene polymorphism of Guizhou White xiang pig,the polymorphism of directly sequence(2 473 bp)of apoA5 gene was measured with the method of direct sequencing in Guizhou White xiang pig.The results showed that one variable site was detected in the second intron of apoA5 gene in Guizhou White xiang pig,and 11 variable sites were detected in the third exon of apoA 5 gene.In addition,4 mutations took place in the a... |
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| Keywords: | Guizhou White xiang pig aopA5 gene polymorphism |
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