RYRl基因对母猪繁殖性能的影响

用 PCR- RFL P法检测 2 2 5头大约克母猪的 RYR1(ryanodine receptor,RYR1)基因 ,它具有 NN、Nn和 nn3种基因型 ,其频率分别为 0 .76、0 .14和 0 .10 ;等位基因 N和 n的基因频率分别为 0 .83和 0 .17。该基因处于遗传不平衡状态 (P<0 .0 1)。具有 NN、Nn和 nn基因型母猪第 1胎产仔数分别为 10 .2 1、9.6 2和 8.2 2头 ;断奶仔猪数分别为9.2 1、8.13和 7.11头。等位基因 n使仔猪断奶应激效应具上升趋势 ,对增重有不利影响 ;降低母猪的产仔数和仔猪成活率 ,对繁殖性能有不良的遗传效应 ,有必要从母猪群中清除该等位基因。

Effects of RYR1 Gene on Reproductive Traits of Large White Sow

Two hundred and twenty five Large White sows were genotyped for ryanodine receptor gene(RYR1) by restriction fragment length polymorphism analysis(RFLP).The genotype frequencies of NN,Nn and nn were 0 76,0 14 and 0 10,respectively.The frequency of n allele was 0 17 and that of N allele was 0 83.RYR1 gene in this sow population was in genetic disequilibrium( P <0 01).For NN,Nn and nn sows,the litter sizes of first parity averaged were 10 21,9 62 and 8 22,respectively,the litter sizes at weaning were 9 21,8 13 and 7 11.The result showed that n allele increased piglet weaning stress,decreased litter size,the number born alive and growth rate of litters.It was concluded that n allele has negative effect on reproduction performance and piglet growth.We should eliminate n allele in our sow groups.