肛周脓肿患者121份病原菌分布及药敏试验结果分析

目的 了解肛周脓肿病原学分布及其药敏情况，以指导临床抗菌药物的选择，从而提高疗效。方法 回顾性分析我院2016年全年肛周脓肿患者细菌分布及药敏试验结果。结果 全年共送检145份标本，24份细菌未生长，其余121份标本共分离出124株细菌，其中3份标本中培养出2种细菌。124株细菌中大肠埃希氏菌占比高达72.58%。其次为肺炎克雷伯菌和奇异变形菌，合占18.55%。全部菌株对氨苄西林、复方新诺明、氨苄西林/舒巴坦等10种抗生素的耐药率超过25.81%，对美罗培南、氨曲南、亚胺培南等8种抗生素的耐药率最低。多重耐药菌检出率为20.16%。结论 肛周脓肿感染的病原菌以革兰氏阴性杆菌为主，其中大肠埃希氏菌占绝大多数，且菌株的多重耐药菌检出率较高。临床上可选用头霉素类，如头孢西丁、头孢替坦等对β-内酰胺酶有高度稳定性的抗生素。

Analysis of Pathogenic Bacteria Distribution and Drug Sensitivity Test from 121 Reports in Perianal Abscess Patients

Objective To guide the selection of clinical antibacterial agents through investigating the pathogenic bacteria distribution and drug sensitivity in perianal abscess patients, thereby enhancing efficacy.Methods The pathogenic bacteria distribution and drug sensitivity in perianal abscess patients in our hospital in 2016 were retrospectively analyzed.Results A total of 145 specimens were submitted and 24 bacteria didn''t grow. 124 strains of bacteria were isolated from the remaining 121 specimens, 2 of which were cultured in 3 specimens. Among them, Escherichia coli accounted for 72.58%. Klebsiella pneumoniae and Proteus mirabilis accounted for 18.55%. The resistance rate of all strains to 10 kinds of antibiotic, such as ampicillin, sulfamethoxazole, ampicillin/sulbactam etc. was over 25.81%, Resistant to 8 kinds of antibiotic, such as meropenem, aztreonam, imipenem, etc. was the lowest. The detection rate of multi drug resistant bacteria was 20.16%.Conclusion The main pathogenic bacteria of perianal abscess are gram negative bacilli, among which Escherichia coli is the majority, Moreover, the detection rate of multidrug-resistant bacteria was higher. In clinic, we could choose cephamycins, such as cefoxitin, cefotetan, which show high stability on beta lactamase antibiotics.