Lawsonia intracellularis proliferative enteropathy in a weanling foal,with a tentative histological diagnosis of lymphocytic plasmacytic enteritis |
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Authors: | K. J. Allen G. R. Pearson D. Fews S. McOrist T. J. Brazil |
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Affiliation: | 1. Department of Clinical Veterinary Science, University of Bristol, Langford House, Langford, Bristol BS40 5DU;2. School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Leicestershire LE12 5RD;3. Equine Medicine On The Move Ltd, 19 Fosseway Drive, Moreton-in-Marsh, Gloucestershire GL56 0DU, UK. |
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Abstract: | This Case Report describes a weanling filly with protein-losing enteropathy associated with Lawsonia intracellularis infection. This was diagnosed on the basis of a significant antibody response and a positive faecal PCR result. The histopathological lesion observed in proliferative enteropathy is mucosal hyperplasia, commonly affecting the ileum and colon in foals. Duodenal biopsies obtained from this filly revealed a lymphocytic plasmacytic infiltrate. The filly recovered completely following treatment with erythromycin and no additional medication was administered to treat the lymphocytic plasmacytic infiltrate. This Case Report suggests that lymphocytic plasmacytic infiltrates observed on duodenal biopsies may represent a nonspecific intestinal immune response. |
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Keywords: | horse Lawsonia intracellularis lymphocytic-plasmacytic enteritis |
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