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A new arylnaphthalene lignan from Knema furfuracea
Authors:Noppadon Rangkaew  Rutt Suttisri  Masataka Moriyasu  Kazuko Kawanishi
Institution:aDepartment of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand;bDepartment of Natural Medicinal Chemistry, Kobe Pharmaceutical University, 4-19-1 Motoyama-kitamachi, Higashinada-ku, Kobe 658-8558, Japan
Abstract:A new arylnaphthalene lignan, named furfuracin (1), was isolated from the leaves of Knema furfuracea (Myristicaceae), whereas 7 known compounds including (+)-trans-1,2-dihydrodehydroguaiaretic acid, fragransin A2, biochanin A, gingkolic acid, anarcardic acid, 2-hydroxy-6-(12-phenyldodecyl)-benzoic acid and 2-hydroxy-6-(12-phenyldodecen-8′Z-yl)-benzoic acid were obtained from its stems. The structure of the new lignan was established by analysis of spectroscopic data (UV, IR, MS and NMR).
Keywords:Knema furfuracea  Lignan  Furfuracin
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