| 表观遗传修饰对转基因和克隆胚早期发育的影响研究进展 |
| |
| 引用本文： | 张进荣,马晶晶.表观遗传修饰对转基因和克隆胚早期发育的影响研究进展[J].中国牛业科学,2009,35(3). |
| |
| 作者姓名： | 张进荣 马晶晶 |
| |
| 作者单位： | 1. 咸阳市秦都区农村能源办公室,陕西,咸阳,712001
2. 西北农林科技大学动物医学院,陕西,杨凌,712100 |
| |
| 摘 要： | 表观遗传修饰在基因表达和克隆胚的早期发育方面有重要作用.本文从DNA甲基化、组蛋白修饰、染色质重塑和非编码RNA调控方面综述了表观遗传的发生机制及其对转基因和克隆胚早期发育的影响.该文对表观遗传的研究有重要的指导作用.
|
| 关 键 词： | 表观遗传修饰 DNA甲基化 组蛋白修饰 基因印记 核重编程 |
Advancement of Epigenetic Modifications Regulate Influences Transgenic and the early Development of Cloned Embryo |
| |
| ZHANG Jin-rong,MA Jing-jing.Advancement of Epigenetic Modifications Regulate Influences Transgenic and the early Development of Cloned Embryo[J].China Cattle Science,2009,35(3). |
| |
| Authors: | ZHANG Jin-rong MA Jing-jing |
| |
| Institution: | 1.Xianyang Qindu district rual nenerge office;Xianyang;Shananxi;712001;China;2.Collage of Animal Medicine;Northwest A & F University;Yangling;712100;China |
| |
| Abstract: | Epigenetic modifications plays an important role in gene expression and the early development of cloned embryo.From four aspects including DNA methylation,histone acetylation,chromatin remodeling and non-coding RNAs,this article discribed the mechanism of epigenetic modifications and its effects on transgene and the early development of cloned embryo.The article has great instructional significants for researching epigenetic modifications. |
| |
| Keywords: | Epigenetic modifications DNA methylation histone acetylation gene imprinting nuclear reprogramming |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中国牛业科学》浏览原始摘要信息 |
| 点击此处可从《中国牛业科学》下载免费的PDF全文 |
