阿德呋啉对球虫耐药株的疗效

观察阿德呋啉对巢湖、霍邱、定远3地球虫的治疗效果及雏鸡增重的影响。结果显示巢湖株中，氯羟吡啶组抗球虫指数（ACI：anti—coecidialindex）值为183．26，敏感，其余组均完全耐药；霍邱株中，妥曲珠利组ACI值为180．48，敏感，其余组呈部分或完全耐药；而定远株对5种抗球虫药均不敏感。与阳性对照组相比，除霍邱株拌料给药组外，其余阿德呋啉给药组ACI值均高于180，对三地鸡球虫病均有良好的疗效；与对照组相比，巢湖和定远株感染组中拌料给药组增重效果明显，饮水给药组次之，而霍邱株均接近阴性对照组，且阿德呋啉给药组的饲料转化率均高于对照组。试验结果表明：3种虫株对试验所用5种抗球虫药已形成交叉或多重耐药，阿德呋啉对上述虫株有较好的抑杀效果，且具有促生长作用。

The effect of adprin on coccidia resistant strains

The efficacy of adprin to the multi-drug-resistance strain on chicks was observed. Re- sults,showed that in the Chaohu strain, the ACI of the clopidol group was 183.26, and the other groups all were definited as complete resistance;in the Huoqiu strain, the ACI of the toltrazuril group was 180.48, the other groups were resistant partially or completely to the drugs; the Din- gyuan strains were found to be insensitive to five anti-coccidial drugs. Compared with positive con- trol groups,except for the medicated group mixed Huoqiu strain into forage all the ACI of other adprin groups were higher than 180 which had a good efficacy on the coccidiosis in chicken of these three regions. Compared with control groups, the medicated group mixed Chaohu strain and Din- gyuan strain into forage had an significant effect on weight gain,the mediated group administed in water was second while all the Huoqiu strain were close to the negative groups;all the feed conver- sion efficiency of adprin groups was higher than the control groups. The result showed that the cross or multiple resistance of the three strains to five anti-coccidial drugs used in the experiment was developed ; the effect of the adprin on inhibiting and killing the above-mentioned strains was significant and promoted effects on chicken growth.