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THE EFFECTS OF A UNILATERAL ULTRASOUND-GUIDED RENAL BIOPSY ON RENAL FUNCTION IN HEALTHY SEDATED CATS
Authors:Wm Tod   Drost  DVM   George A.  Henry  DVM   James H.  Meinkoth  DVM  MS  PnD   J. Paul  Woods  DVM  MS   Mark E.  Payton  PhD   Carolyn  Rodebush  ASRT
Affiliation:Department of Veterinary Clinical Sciences, Oklahoma State University, Stillwater 74078, USA.
Abstract:Complications of renal biopsies are well documented except for the change in renal function after a biopsy. Eighteen healthy, adult cats were divided into two groups (n = 9 cats/group). For the measurement of global and split renal function, Group 1 used the renal uptake of 99mTc-DTPA and Group 2 used the renal uptake of 99mTc-MAG3. Scintigraphic data were collected on days (-4), (-3), 0, 1, 2, and 4 post renal biopsy. Using ultrasound guidance, biopsies were taken from the right renal cortex on dO, before acquiring scintigraphic images. P - values less than 0.10 were considered significant due to the limited number of observations. The only statistically significant change (p = 0.08) in global renal function detected was by day following a unilateral renal biopsy. Cats imaged using 99mTc-MAG3 had discernible liver activity. A unilateral, ultrasound guided renal biopsy has minimal effect on renal function in normal, healthy sedated cats.
Keywords:Cat    kidneys    ultrasound guided biopsy    renal function    scintigraphy    99mTc-DTPA    99mTc-MAG3
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