| 相邻位点碱基突变的熵性质 |
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| 引用本文： | 张银霞,曹钻,袁志发,陶士珩. 相邻位点碱基突变的熵性质[J]. 浙江大学学报(农业与生命科学版), 2010, 36(1): 43. DOI: 10.3785/j.issn.1008-9209.2010.01.007 |
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| 作者姓名： | 张银霞 曹钻 袁志发 陶士珩 |
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| 作者单位： | 1. 西北农林科技大学,理学院,陕西,杨凌,712100
2. 西北农林科技大学,生物信息学研究中心,陕西,杨凌,712100;西北农林科技大学,生命科学学院,陕西,杨凌,712100 |
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| 摘 要： | 为了在分子水平上探讨2相邻位点碱基突变的熵性质,在双参数模型下建立有限长DNA序列2相邻位点碱基突变的微分方程模型,得出了16种碱基组成的概率随世代变化的函数关系式,证明2相邻位点碱基突变具有保熵性,生物是朝着熵增方向即多样性增加的方向进化的;阐明了在单参数模型下相邻位点碱基突变的熵性质亦是如此;该结论也适用于3个相邻位点以及更多相邻位点碱基突变的情况。并利用Matlab软件进行2相邻位点碱基突变的计算机模拟,直观地验证了所得的理论结果。
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| 关 键 词： | Shannon信息熵 单参数模型 双参数模型 生物多样性 |
Entropy characters of neighboring sites mutation |
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| ZHANG Yin-xia,CAO Zuan,YUAN Zhi-fa,TAO Shi-heng. Entropy characters of neighboring sites mutation[J]. Journal of Zhejiang University(Agriculture & Life Sciences), 2010, 36(1): 43. DOI: 10.3785/j.issn.1008-9209.2010.01.007 |
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| Authors: | ZHANG Yin-xia CAO Zuan YUAN Zhi-fa TAO Shi-heng |
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| Affiliation: | ZHANG Yin-xia1,CAO Zuan1,YUAN Zhi-fa1,TAO Shi-heng2,3(1.College of Science,Northwest A&F University,Yangling,Shaanxi 712100,China,2.Bioinformatics Center,3.College of Life Sciences,China) |
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| Abstract: | For discussing the entropy characters of two neighboring sites mutation at the molecular level,a set of differential equations were founded about two neighboring sites mutations of a DNA sequences with limited length,based on the two-parameter model,and the function was got which could describe the processes of variation in quantity of 16 kinds of base combinations in the DNA sequence.The conclusions were proved that neighboring sites mutations maintained their entropy and species evolve in the direction of... |
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| Keywords: | Shannon entropy one-parameter model two-parameter model biodiversity |
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