Naloxone antagonism of the thermoregulatory effects of phencyclidine |
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Authors: | S D Glick R A Guido |
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Abstract: | Phencyclidine elicits hyperthermia at low doses and hypothermia at high doses in rats. Naloxone antagonizes both effects. Phencyclidine's effects on thermo-regulation are probably mediated by an interaction with a mu opiate receptor. |
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