Adult Multipotent Stromal Cell Technology for Bone Regeneration: A Review |
| |
| Authors: | Mandi J. Lopez DVM MS PhD Diplomate ACVS Patrick R. Daigle |
| |
| Affiliation: | Laboratory for Equine and Comparative Orthopedic Research, Veterinary Clinical Sciences Department, School of Veterinary Medicine, Louisiana State University, , Baton Rouge, LA |
| |
| Abstract: | Since the discovery of bone marrow derived stromal cell osteogenesis in the 1960s, tissue engineering with adult multipotent stromal cells (MSCs) has evolved as a promising approach to restore structure and function of bone compromised by injury or disease. To date, accelerated bone formation with MSCs has been demonstrated with a variety of tissue engineering strategies. Though MSC bone tissue engineering has advanced over the last few decades, limitations to clinical translation remain. A current review of this promising field is presented with a specific focus on equine investigations. |
| |
| Keywords: | |
|
|
