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The use of nuclear imaging for a mixed C cell microfollicular carcinoma of the thyroid gland in a mature horse
Authors:M N Saulez  A Viljoen  U Kafka  L Rubio‐Martinez  E van Wilpe  J Steyl
Institution:1. Section of Equine Medicine,;2. Section of Diagnostic Imaging;3. Section of Equine Surgery, Department of Companion Animal Clinical Studies;4. Electron Microscopy Unit;5. Section of Pathology, Department of Paraclinical Studies, Faculty of Veterinary Science, University of Pretoria, South Africa
Abstract:A 15‐year‐old Boerperd stallion presented for thyroid enlargement associated with inappetance. Ultrasonographic examination of the thyroid gland revealed an enlarged left lobe, which, on cytological examination, contained numerous anaplastic cells. A mixed C cell microfollicular thyroid carcinoma was diagnosed following histopathological examination of the excisional biopsy specimen. In order to determine metastasis, pulmonary radiographs revealed a poorly‐marginated soft tissue opacity caudo‐dorsal to the cardiac silhouette. Thyroid and pulmonary scintigraphy was performed comparing 99mTc‐sestamibi with 99mTc‐pertechnetate and no metastasis was detectable. Following hemithyroidectomy, the stallion made a full recovery without the need for neoadjuvant chemotherapy. Six months later, repeated thyroid and pulmonary scintigraphy using 99mTc‐sestamibi was normal.
Keywords:horse  carcinoma  99mTc‐sestamibi  99mTc‐pertechnetate  scintigraphy  thyroid
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