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The role of lipoteichoic acids on the adherence of Streptococcus equi to epithelial cells
Authors:Satish K Srivastava  Donald A Barnum
Institution:Department of Veterinary Microbiology and Immunology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada
Abstract:The effect of the presence of lipoteichoic acids (LTA) on a strain of Streptococcus equi was investigated. The LTA were extracted in a crude form from the S. equi strain and were found to sensitize sheep red blood cells so that they agglutinated with antibodies specific to purified LTA of group A streptococci. The crude LTA preparation was also able to inhibit the specific haemagglutination reaction involving group A streptococcal LTA and LTA antibodies. Neither the purified LTA from group A streptococci nor the anti-LTA serum interfered with the adherence of S. equi to equine epithelial cells.
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