Immunohistochemical characteristics of canine aortic and carotid body tumours |
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Authors: | Brown P J Rema A Gartner F |
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Institution: | Department of Clinical Veterinary Science, University of Bristol Veterinary School, Langford, Bristol, BS40 5DU, UK. p.brown@bristol.ac.uk |
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Abstract: | In an immunohistochemical study of 25 canine chemodectomas, 17 tumours were stained with antisera to neurone specific enolase and the same number were stained for synaptophysin; a single tumour was stained for S100. Staining for Ki-67 occurred in 18 cases; the Ki-67-labelling index and the intensity of immunostaining was increased in more pleomorphic and malignant tumours, as assessed on histological grounds. Immunohistochemistry did not aid in recognition of less well-differentiated tumours. |
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