Orexin and orexin receptor like peptides in the gastroenteric tract of Gallus domesticus: An immunohistochemical survey on presence and distribution |
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Authors: | N Arcamone L D’Angelo P de Girolamo C Lucini A Pelagalli L Castaldo |
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Institution: | 1. Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Italy;2. Department of Advanced Biomedical Sciences, University of Naples Federico II, Italy;3. Institute of Biostructures and Bioimages, National Research Council, Naples, Italy |
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Abstract: | This study reports the immunohistochemical localization and distribution of orexin A and B-like and their receptors-like peptides in the gastroenteric tract of chicken. The immunoreactivity is distributed in endocrine cells, nerve fibers and neurons, both in the stomach and intestine, and shows a discrete conformity with the data till now reported for Mammals. Our study suggests a possible participation of orexin-like peptides in the modulation of chicken gastroenteric activities and the preservation of their main distribution compared to Mammals. Western blot analysis has confirmed the presence of prepro-orexin and both receptors in the examined tissues. |
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Keywords: | Orexins Orexins receptors Immunohistochemical study Gastroenteric tract Gallus domesticus |
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