| 桦褐孔菌粗多糖对急性感染弓形虫小鼠的存活时间及SOD的影响 |
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| 引用本文： | 刘妍,鞠玉琳,刘利本.桦褐孔菌粗多糖对急性感染弓形虫小鼠的存活时间及SOD的影响[J].中国兽医杂志,2011,47(7). |
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| 作者姓名： | 刘妍 鞠玉琳 刘利本 |
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| 作者单位： | 延边大学农学院动物医学系,吉林 龙井,133400 |
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| 基金项目： | 国家自然科学基金(30860211) |
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| 摘 要： | 为探讨桦褐孔菌粗多糖(IOCP)对急性感染弓形虫小鼠的存活时间及血清、心、肝和肺中超氧化物歧化酶(SOD)含量的影响。采用昆明系小鼠80只,随机分为IOCP组、阳性对照组(蒿甲醚)、空白对照组和阴性对照组,每组20只。用RH株弓形虫建立小鼠病理模型,观察小鼠治疗后的存活时间,以及血清、心、肝和肺中SOD含量。结果:IOCP及阳性药物均可延长感染弓形虫小鼠的存活时间;可明显提高小鼠脏器SOD活性;与阳性对照组比较差异显著(P<0.05)。结论:IOCP能延长感染弓形虫小鼠的存活时间,并具有抗氧化损伤作用。
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| 关 键 词： | 桦褐孔菌粗多糖 弓形虫RH株 超氧化物歧化酶 |
Effect of inonotus obliquus coarse polysaccharide against acute toxoplasma gondii infection on SOD in female mice |
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| LIU Yan,JU Yu-lin,LIU Li-ben.Effect of inonotus obliquus coarse polysaccharide against acute toxoplasma gondii infection on SOD in female mice[J].Chinese Journal of Veterinary Medicine,2011,47(7). |
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| Authors: | LIU Yan JU Yu-lin LIU Li-ben |
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| Institution: | LIU Yan,JU Yu-lin,LIU Li-ben(Agricultural College of Yan Bian University,Longjing 133400,China) |
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| Abstract: | To investigate the effect of inonotus obliquus coarse polysaccharide(IOCP) on SOD in mice infected with RH strain of toxoplasma gondii,eighty mice were divided into IOCP group,and the establishment of the blank control group,negative control group and positive control(artemether) group.The mice model was made by RH strain of toxoplsma gondii,SOD activities in mice serum,heart,liver and lung were detected.The results showed that IOCP group could delay the invasion time of mice infected by RH strain of toxopl... |
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| Keywords: | inonotus obliquus polysaccharide RH strain of toxoplasma gondii SOD |
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