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脑肠肽ghrelin的研究进展
引用本文:火焱,杨银凤.脑肠肽ghrelin的研究进展[J].中国兽医科技,2006,36(3):252-256.
作者姓名:火焱  杨银凤
作者单位:内蒙古农业大学动物科学与医学学院,内蒙古呼和浩特010018
基金项目:国家自然科学基金项目(30460092)
摘    要:介绍了近年来发现的由28个氨基酸残基组成的ghrelin的来源、分子结构、不同物种间的ghrelin组成差异、分布组织及存在形式,归纳了影响ghrelin分泌的因素,认为ghrelin在调节生长激素的释放、能量代谢、其他激素的分泌和参与调节睡觉一觉醒模式及细胞增殖方面发挥了重要生物学效应。

关 键 词:ghrelin  前原ghrelin  生长激素  酰基化
文章编号:1673-4696(2006)03-0252-05
收稿时间:2005-12-21

Research advances on ghrelin
HUO Yan,YANG Yin feng.Research advances on ghrelin[J].Chinese Journal of Veterinary Science and Technology,2006,36(3):252-256.
Authors:HUO Yan  YANG Yin feng
Abstract:Research advances on the recenrty discovered ghrelin, a natural ligand for growth hormone secretogogue receptor, were reviewed in its origin, molecular structure, distribution and forms in tissues, and differences among 10 species of animals and human beings. The factors affecting the secretion of ghrelin were summarized. It was considered that ghrelln has important physiological effects on the release of growth-hormone, energy metabolism, the secretion of endocrine hormones, sleeping-awaking process and cellular multiplication.
Keywords:ghrelin  preproghrelin  growth-hormone  acylation
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