Effect of the carbamate pesticide Sevin on the intestinal absorption of some nutrients in the teleost fish,Channa Punctatus

The effect of four concentrations (0.1, 1, 10, and 100 ppm) of Sevin on the rate of uptake of two sugars (glucose and fructose) and an aminoacid (tryptophan) by the intestine of the fresh water snake-head fish,Channa punctatus has been investigated. All four concentrations of the pesticide decreased the rate of transport of the three nutrients. No direct relationship could be established between the concentration of Sevin in the medium and decrease in the rate of transport of nutrients, although, increase in the concentration of Sevin reduced the absorption of nutrients by the intestine to a greater extent. Experiments conductedin vivo andin vitro showed that in both cases the pesticide decreased the brush border enzyme activity.