环丙沙星雏鸡中毒试验

分别以0．01％、0．02％及0．04％浓度的环丙沙星给4日龄海兰褐蛋雏鸡连续饮水12d，进行环丙沙星雏鸡人工中毒试验研究，结果表明：0．01％组全程未见明显的临床表现及剖检病变，镜检免疫器官发育不良；0．02％组中后期出现轻微的神经症状及消化道症状，剖检肠黏膜脱落、肾肿、组织器官有轻微的变性、充血、出血病变；0．04％组中后期出现明显的临床症状，并发生急性中毒死亡，剖检及镜检出现广泛性严重的病理变化。

POISON EXPERIMENT OF CIPROFIOXAIN ON CHICKEN

The ciprofioxains concentrations of 0.01%,0.02%and 0.04% were given to four days Hailanhe chicken for 12 days. It was shown that there were no clinical expression and dissection lesion ;but dyspasia of immune organa under microscopic examination was found in the 0.01% group. Slight nervous symptom and digestive system symptom,intestinal mucosa abscission,kidney swelling and slight degeneration,hyperemia and hemorrhage of some tissue organ in the mid-late period in the 0.02% group. Obvious clinical expressions, acute poisoning death and serious pathological lesions were widely found in the 0.04% group.