Bovine viral diarrhea in a newborn calf

Bovine viral diarrhea virus was believed to be the cause of ill-thrift since birth, resulting in death of a Holstein calf. Bovine viral diarrhea virus was isolated from Peyer's patches and mesenteric lymph nodes, but serum neutralizing antibodies were not detected. The lymphoid depletion and myeloid suppression seen in this case may be a factor in the immune system dysfunction described for bovine viral diarrhea. Typical ulcerative lesions within the alimentary tract were not observed.