Comparative Study on the Chemical Composition,Antioxidant Properties and Hypoglycaemic Activities of Two <Emphasis Type="Italic">Capsicum annuum</Emphasis> L. Cultivars (<Emphasis Type="Italic">Acuminatum</Emphasis> small and <Emphasis Type="Italic">Cerasiferum</Emphasis>) |
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| Authors: | Rosa Tundis Monica R Loizzo Federica Menichini Marco Bonesi Filomena Conforti Giancarlo Statti Damiano De Luca Bruno de Cindio Francesco Menichini |
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| Institution: | (1) Department of Pharmaceutical Sciences, Faculty of Pharmacy and Nutrition and Health Sciences, University of Calabria, 87036 Rende, CS, Italy;(2) Department of Engineering Modeling, University of Calabria, 87036 Arcavacata di Rende, CS, Italy;(3) AIFA, Italian Medicines Agency, 00187 Roma, Italy;(4) CALAB, Laboratorio Chimico Merceologico della Calabria, 87040 Montalto Uffugo, CS, Italy;(5) Department of Pharmaceutical Sciences, Faculty of Pharmacy, Nutrition and Health Sciences, University of Calabria, 87036 Rende, CS, Italy |
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| Abstract: | The present study aimed to evaluate for the first time the phenols, flavonoids, carotenoids, capsaicin and dihydrocapsaicin
content and the antioxidant and hypoglycemic properties of Capsicum annuum var. acuminatum small and C. annuum var. cerasiferum air-dried fruits. The ethanol extract of C. annuum var. acuminatum small, characterized by the major content of total poliphenols, flavonoids, carotenoids and capsaicinoids, showed the highest
radical scavenging activity (IC50 of 152.9 μg/ml). On the contrary, C. annuum var. cerasiferum showed a significant antioxidant activity evaluated by the β-carotene bleaching test (IC50 of 3.1 μg/ml). The lipophilic fraction of both C. annuum var. acuminatum and C. annuum var. cerasiferum exhibited an interesting and selective inhibitory activity against α-amylase (IC50 of 6.9 and 20.1 μg/ml, respectively). |
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