Effects ofIn Vitro degradation on the weight loss and tensile properties of PLA/LPCL/HPCL blend fibers |
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Authors: | Cheol Soo Yoon Dong Sun Ji |
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Institution: | (1) Department of Textile Engineering, Dankook University, 140-714 Seoul, Korea |
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Abstract: | PLA/LPCL/HPCL blend fibers composed of poly (lactic acid) (PLA), low molecular weight poly (ɛ-caprolactone) (LPCL), and high molecular weight poly (ɛ-caprolactone) (HPCL) were prepared by melt blending and spinning for bioabsorbable filament sutures. The effects of blending
time and blend composition on the X-ray diffraction patterns and tensile properties of PLA/LPCL/HPCL blend fibers were characterized
by WAXD and UTM. In addition, the effect ofin vitro degradation on the weight loss and tensile properties of the blend fibers hydrolyzed during immersion in a phosphate buffer
solution at pH 7.4 and 37°C for 1–8 weeks was investigated. The peak intensities of PLA/LPCL/HPCL blend fibers in X-ray diffraction
patterns decreased with an increase of blending time and LPCL contents in the blend fibers. The weight loss of PLA/LPCL/HPCL
blend fibers increased with an increase of blending time, LPCL contents, and hydrolysis time while the tensile strength and
modulus of the blend fibers decreased. The tensile strength and modulus of the blend fibers were also found to be increased
with an increase of HPCL contents in the blend fibers. The optimum conditions to prepare PLA/LPCL/HPCL blend fibers for bioabsorbable
sutures are LPCL contents of 5 wt%, HPCL contents of 35 wt%, and blending time of 30 min. The strength retention of the PLA/LPCL/HPCL
blend fiber prepared under optimum conditions was about 93.5% even at hydrolysis time of 2 weeks. |
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Keywords: | PLA LPCL HPCL Bioabsorbable sutures Hydrolysis |
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