| 脂质体用大豆卵磷脂的制备及质量评价 |
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| 引用本文： | 穆筱梅,钟振声,杨梅.脂质体用大豆卵磷脂的制备及质量评价[J].大豆科学,2007,26(2):250-253. |
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| 作者姓名： | 穆筱梅 钟振声 杨梅 |
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| 作者单位： | 仲恺农业技术学院化学与化工系,广东,510325;华南理工大学化学学院,广州,510641 |
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| 摘 要： | 以大豆磷脂为原料,用溶剂-超临界CO2萃取法制备脂质体用高纯度大豆卵磷脂,并对其质量进行评价.结果表明大豆卵磷脂的含量是94.98%,丙酮不溶物的含量是99.0%,酸值是20.6KOH mg/g,干燥失重是0.63%,己烷不溶物的含量0.18%,砷盐的含量是2.1×10-6 %,重金属的含量是2.0×10-5 %.以精制的大豆磷脂为原料制备的脂质体,在透射电镜下呈圆球状.粒径为164 nm,Zeta电位为-28.50 mv,包封率是32.43%.
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| 关 键 词： | 大豆卵磷脂 溶剂萃取 超临界CO2萃取 脂质体 |
| 文章编号： | 1000-9841(2007)02-0250-04 |
| 修稿时间： | 2006年6月16日 |
PREPARATION AND QUALITY EVALUATION OF SOYBEAN PHOSPHATIDYLCHOLINE AS LIPOSOMAL MATERIAL |
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| MU Xiao-mei,ZHONG Zhen-sheng,YANG Mei.PREPARATION AND QUALITY EVALUATION OF SOYBEAN PHOSPHATIDYLCHOLINE AS LIPOSOMAL MATERIAL[J].Soybean Science,2007,26(2):250-253. |
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| Authors: | MU Xiao-mei ZHONG Zhen-sheng YANG Mei |
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| Abstract: | High-purity soybean phosphatidylcholines(SPC) as liposomal material was prepared from soybean phospholipids with a method combined super critical carbon dioxide extraction and solvent extraction.The results of the quality evaluation showed that the SPC was separated with94.98% purity,the content of aceton-insoluble matter,hexane-insoluble matter,heavy metals and arsenic were respectively 99%,0.18%,2.0 10-5% and 2.1 10-6%,the acid value was 20.6 mg of potassium hydroxide,loss on drying of SPC was 0.63%.The liposome made with SPC showed spherical shape,its main particles was164 nm,Zeta potential was-28.50 mv,and the entrapment efficiency was 32.43%. |
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| Keywords: | Soybean phosphatidylcholines Solvent extraction Supercritical carbon dioxide extraction and liposome |
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