| 人参叶口服液对大鼠的亚慢性毒性试验 |
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| 引用本文： | 郭迎春,邸静,胡松华,杨英,倪敬轩,王宇.人参叶口服液对大鼠的亚慢性毒性试验[J].动物医学进展,2011,32(5):59-63. |
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| 作者姓名： | 郭迎春 邸静 胡松华 杨英 倪敬轩 王宇 |
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| 作者单位： | 郭迎春,邸静,杨英,倪敬轩,王宇,GUO Ying-chun,DI Jing,YANG Ying,NI Jing-xuan,WANG Yu(内蒙古农业大学兽医学院,内蒙古呼和浩特,010018);胡松华,HU Song-hua(浙江大学动物科学学院,浙江杭州,310000) |
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| 基金项目： | 国家"十一五"科技支撑计划课题:"中兽药免疫增强剂及疫苗佐剂的研制与开发"(2008BADB4B06-5)子课题"中药皂苷类、禽用口服免疫增强剂的安全性研究" |
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| 摘 要： | 将Wistar大鼠随机分为4组,3个剂量组(以人参皂苷计)分别按40、80、160 mg/kg体重给大鼠灌胃,对照组给予同体积生理盐水,1次/d,连续28 d,记录大鼠毒副反应.停药后继续观察14 d,测试大鼠体重、血液学指标、血液生化学指标、脏器指数.结果表明,各剂量组大鼠与对照组比较,给药期与恢复期的体重增长,血液...
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| 关 键 词： | 人参叶口服液 亚慢性毒性 大鼠 |
Sub-chronic Toxicity Test of Ginseng Leaf Oral Liquid in Rats |
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| GUO Ying-chun,DI Jing,HU Song-hua,YANG Ying,NI Jing-xuan,WANG Yu.Sub-chronic Toxicity Test of Ginseng Leaf Oral Liquid in Rats[J].Progress In Veterinary Medicine,2011,32(5):59-63. |
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| Authors: | GUO Ying-chun DI Jing HU Song-hua YANG Ying NI Jing-xuan WANG Yu |
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| Institution: | 1(1.College of Veterinary Medicine,Inner Mongolia Agricultural University,Hohhot,Inner Mongolia,010018,China;2.College of Animal Science,Zhejiang University,Hangzhou,Zhejiang,310000,China) |
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| Abstract: | The Wistar rats were randomly divided into 4 groups,the three experimental groups were given ginseng leaf oral liquid in doses of 40,80,160 mg/kg by gastric lavage for 28 days and were observed after stopping administration for 14 days.The control group was given the same amount of normal saline.The body weight,indexes of hematology and blood bio-chemistry,weight coefficients of organs were observed.Results showed that the body weight,indexes of hematology and blood biochemistry,weight coefficients of organs were not significantly different from that in the control group(P>0.05).Results confirmed that rats had no adverse reaction after being given ginseng leaf oral liquid for 28 days,and had no delayed adverse reaction in 14 days’recovery. |
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| Keywords: | ginseng leaf oral liquid sub-chronic toxicity rat |
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