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不同保种时间及复苏代次弓形虫对小鼠致病性研究
引用本文:曾艳波,朱顺海,韩红玉,董辉,姜连连,赵其平,马卫娇,程军,黄兵.不同保种时间及复苏代次弓形虫对小鼠致病性研究[J].动物医学进展,2011,32(6):55-59.
作者姓名:曾艳波  朱顺海  韩红玉  董辉  姜连连  赵其平  马卫娇  程军  黄兵
作者单位:中国农业科学院上海兽医研究所,农业部动物寄生虫学重点开放实验室,上海,200241
基金项目:农业公益性行业科研专项
摘    要:为了评价液氮冻存不同时间后及在小鼠体内复苏不同代次的弓形虫速殖子感染小鼠致病性的研究,通过比较感染处理后的弓形虫小鼠健康及存活状况,筛选出更佳的液氮冻存时间和合适复苏代次,对于建立小鼠急性弓形虫感染模型及弓形虫致病机理等具有重要意义.通过腹腔注射不同保种时间(2、4、6月)和不同复苏代次(1、2、3代)弓形虫速殖子,观...

关 键 词:弓形虫  速殖子  保种时间  复苏代次  致病性

Pathogenicity of Toxoplasma gondii with Different Recovery Generations and Cryopreserved Time
ZENG Yan-bo,ZHU Shun-hai,HAN Hong-yu,DONG Hui,JIANG Lian-lian,ZHAO Qi-ping,MA Wei-jiao,CHENG Jun,HUANG Bing.Pathogenicity of Toxoplasma gondii with Different Recovery Generations and Cryopreserved Time[J].Progress In Veterinary Medicine,2011,32(6):55-59.
Authors:ZENG Yan-bo  ZHU Shun-hai  HAN Hong-yu  DONG Hui  JIANG Lian-lian  ZHAO Qi-ping  MA Wei-jiao  CHENG Jun  HUANG Bing
Institution:ZENG Yan-bo,ZHU Shun-hai,HAN Hong-yu,DONG Hui,JIANG Lian-lian,ZHAO Qi-ping,MA Wei-jiao,CHENG Jun,HUANG Bing(Shanghai Veterinary Research Institute,Chinese Academy of Agricultural Science,Key Laboratory for Animal Parasitology of Ministry of Agriculture,Shanghai,200241,China)
Abstract:In order to evaluate the pathogenicity of Toxoplasma gondii which were cryopreserved in liquid nitrogen for different time and recovered for different generations in mice,the health status and survival condition of the infected mice were observed and compared.It would be important to establish the acute murine toxoplasmosis model and the pathogenesis.T.gondii tachyzoites which were cryopreserved for different time(2,4 and 6 months) were intraperitoneal injected to mice then recovered for different generatio...
Keywords:Toxoplasma gondii  tachyzoite  cryopreserved time  recovery generation  pathogenicity  
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