半胱胺螯合锌对育肥猪免疫性能、抗氧化能力、血清生化指标及肠道微生物的影响

本试验旨在研究饲粮中不同添加量的半胱胺螯合锌(Zn-CS)对育肥猪免疫性能、抗氧化能力、血清生化指标及肠道微生物的影响。选取90头体重为(64.67±1.15)kg的健康育肥猪,随机分为5组,每组3个重复,每个重复(圈)6头。对照组饲喂基础饲粮,试验组分为Ⅰ、Ⅱ、Ⅲ、Ⅳ组,分别饲喂在基础饲粮中添加60、90、120、150 mg/kg Zn-CS的试验饲粮。结果表明:1)与对照组相比,Ⅰ、Ⅱ组血清免疫球蛋白A(IgA)含量显著提高(P<0.05)。2)与对照组相比,Ⅲ、Ⅳ组血清丙二醛含量显著降低(P<0.05),Ⅱ、Ⅲ、Ⅳ组血清总抗氧化能力显著提高(P<0.05)。3)与对照组相比,Ⅱ组血清生长激素含量显著提高(P<0.05),Ⅱ组血清生长抑素含量显著降低(P<0.05),Ⅱ、Ⅲ、Ⅳ组血清胰岛素含量显著提高(P<0.05)。4)各组在门水平上相对丰度超过1%的优势菌门有厚壁菌门、变形菌门、拟杆菌门,各组在属水平上相对丰度超过1%的优势菌属有梭菌属、肠杆菌属、Romboutsia、Turicibacter、Terrisporobacter、放线菌属。由此可见,饲粮中添加Zn-CS能够提高育肥猪免疫性能与抗氧化能力。在本试验条件下,建议Zn-CS在育肥猪饲粮中的适宜添加量为120 mg/kg。

Effects of Cysteamine Chelated Zinc on Immunity Function,Antioxidant Capacity,Serum Biochemical Indexes and Intestinal Microflora of Finishing Pigs

This experiment was conducted to investigate the effects of the supplemental levels of cysteamine chelated zinc(Zn-CS)on the immunity function,antioxidant capacity,serum biochemical indexes and intestinal microflora of finishing pigs.A total of 90 healthy finishing pigs with an average body weight of(64.67±1.15)kg were randomly allocated to 5 groups with 3 replicates of 6 pigs.The pigs in control group were fed a basal diet,and those in the experimental groups were divided into groupsⅠ,Ⅱ,ⅢandⅣ,and fed the basal diet with different supplemental levels of Zn-CS(60,90,120 and 150 mg/kg).The results showed as follows:1)compared with the control group,the serum immune globulin A(IgA)content in groupsⅠandⅡsignificantly increased(P<0.05).2)Compared with the control group,the serum malondialdehyde content in groupsⅢandⅣsignificantly decreased(P<0.05),and the serum total antioxidant capacity in groupsⅡ,ⅢandⅣsignificantly increased(P<0.05).3)Compared with the control group,the serum growth hormone content in groupⅡsignificantly increased(P<0.05),the serum somatostatin content in groupⅡsignificantly decreased(P<0.05),and the serum insulin content in groupsⅡ,ⅢandⅣsignificantly increased(P<0.05).4)At the level of phylum,the dominant flora with relative abundance of more than 1%of each group was Firmicutes,Proteobacteria and Bacteroidetes.At the level of genus,the dominant flora with relative abundance of more than 1%of each group was Clostridium,Enterobacteriaceae,Romboutsia,Turicion,Terrisporobacter and Actinobacillus.In conclusion,dietary supplemented with Zn-CS can promote the immunity function and antioxidant capacity.Under the conditions of the present experiment,the optimal supplemental level of Zn-CS in the finishing pigs'diet is 120 mg/kg.