A glucosylceramide with antimicrobial activity from the edible mushroom <Emphasis Type="Italic">Pleurotus citrinopileatus</Emphasis> |
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| Authors: | Tian-Xiao Meng Hiroya Ishikawa Kuniyoshi Shimizu Shoji Ohga Ryuichiro Kondo |
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| Institution: | (1) Department of Agro-environmental Sciences, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan;(2) Department of Nutrition and Health Science, Faculty of Human Environmental Science, Fukuoka Women’s University, Fukuoka 813-8529, Japan; |
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| Abstract: | The golden oyster mushroom Pleurotus citrinopileatus is a popular edible mushroom with multifunctional biological activities, but there are a limited number of previous studies
on its chemical composition. This is the first report of the isolation of glucosylceramide with antimicrobial activity from
the fruiting body of this mushroom. This compound was identified as 1-O-β-d-glucopyranosyl-(2S,3R,4E,8E)-2-(2R)-2-hydroxyhexadecanoylamino]-9-methyl-4,8-octadecadiene-1,3-diol. The IC50 value of this compound for the growth of Escherichia coli and Staphylococcus aureus was 275.1 μM (200 μg/ml) and 323.2 μM (235 μg/ml), respectively. |
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