Abstract: | The discovery of the sulfonylurea class of herbicides is one of the most dramatic breakthroughs in herbicide research in several decades. Sulfonylureas possess unprecedented levels of herbicidal activity–as low as 1 g ha?1–very low mammalian toxicity, and very desirable environmental properties. This review will discuss the structure-activity relationships of sulfonylureas, their physical and chemical properties, and their methods of synthesis. |