Insecticidal activity of 3-isoxazolyl methanesulfonates and related compounds

Various methanesulfonates, notably of 3-isoxazolols, exhibit interesting insecticidal activity, especially against Musca domestica and Locusta migratoria. Although the symptoms of poisoning are very similar to those caused by parathion, no correlation between in-vitro inhibition of acetylcholinesterase and insecticidal activity was observed. This is also true for several methanesulfonates of hydroxy-heterocycles and phenols included in this study for comparison.