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植物提取物“JA1”的亚慢性毒性试验
引用本文:赵曼容,程国权.植物提取物“JA1”的亚慢性毒性试验[J].甘肃农业大学学报,1993,28(4):356-358.
作者姓名:赵曼容  程国权
作者单位:甘肃农业大学,甘肃农业大学,甘肃新医药研究所,甘肃新医药研究所 兰州 730070,兰州 730070,兰州 730050,兰州 730050
摘    要:西北资源植物提取物“JAl”的亚慢性毒性试验结果为:当剂量为1/10 LD_(50)时,呈现一定毒性反应;剂量为1/20 LD_(50)时,对体重、一般情况、血象、肝功(SGPT)均无毒性反应,仅肾功(BUN)略受影响;当剂量为1/30 LD_(50)时,各项指标均属正常,为无毒安全剂量。此结果为“JAl”在临床上的应用提供了可靠的依据。

关 键 词:植物提取物JA1  亚慢性毒性试验

Subchronic Poisonous Test of the Plant Extract JAI
Zhao Manrong Jia Huixian Cheng Guoquan Guo Hongyun.Subchronic Poisonous Test of the Plant Extract JAI[J].Journal of Gansu Agricultural University,1993,28(4):356-358.
Authors:Zhao Manrong Jia Huixian Cheng Guoquan Guo Hongyun
Institution:Zhao Manrong~1 Jia Huixian~1 Cheng Guoquan~2 Guo Hongyun~2
Abstract:The subchronic poisonous test of JAI was conducted on mice. The results obtained revealed that in the dosage of 1/10 LD_(50) it showed some poisonous effects and that in the dosage of 1/20 LD_(50) it had no poisonous effects on body weight, general conditions, blood picture and liver functions (SGPT); only the kidney functions were slightly affected. In the dosage of 1/30 LD_(50) all the indices were normal, indicating that this dosage might be poisonless.
Keywords:subchronic poisonous test  plant extract JAI    
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