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五种不同地理株柔嫩艾美耳球虫免疫保护性比较
引用本文:张伟信,张西臣,李建华.五种不同地理株柔嫩艾美耳球虫免疫保护性比较[J].中国预防兽医学报,2006,28(4):454-456.
作者姓名:张伟信  张西臣  李建华
作者单位:1. 解放军军需大学,军事兽医系,吉林,长春,130062;塔里木大学,动物科技学院,新疆,阿拉尔,843300
2. 解放军军需大学,军事兽医系,吉林,长春,130062
基金项目:国家高技术研究发展计划(863计划)
摘    要:用五个不同地理株的柔嫩艾美耳球虫(Eimeria tenella),即:广州株、保定株、长春株、北京株、沈阳株,对12日龄雏鸡分别进行免疫攻虫。通过OPG计数,粪便计分,盲肠病变计分,增重测定,计算保护率。结果发现不同地理株球虫的免疫保护率有明显差异,广州株80.2%〉保定株73.2%〉长春株68.4%〉北京株63.8%〉沈阳株51.0%。其中广州株比其他虫株有显著保护率(P〈0.01)。免疫后的雏鸡抽血进行CD4^+、CD8^+T细胞检测,结果各株均能引起两种T细胞数量增加,表明CD4^+、CD8^+T细胞在球虫免疫中起着重要作用。

关 键 词:  柔嫩艾美耳球虫  免疫保护性
文章编号:1008-0589(2006)04-0454-03
收稿时间:2005-01-12
修稿时间:2005年1月12日

Comparison on immunoprotective of the different geographic Eimeria tenella to chicken
ZHANG Wei-xin,ZHANG Xi-chen,LI Jian-hua.Comparison on immunoprotective of the different geographic Eimeria tenella to chicken[J].Chinese Journal of Preventive Veterinary Medicine,2006,28(4):454-456.
Authors:ZHANG Wei-xin  ZHANG Xi-chen  LI Jian-hua
Institution:1, Faculty of Animal Sciences, Quartermaster University of PLA, Changchun 130062, China ; 2. College of Animal Science and Technology, Tarim University, Alar 843300, China ;
Abstract:Five strains of E.tenella isolated from Guangzhou,Baoding,Changchun,Beijing,Shenyang were compared on immunogenicity and immunoprotective.The results showed that a great difference in immunoprotective among the different geographic strains,Guangzhou strain 80.2 % > Baodin strain 73.2 % > Changchun strain 68.4 %> Beijing strain 63.8 %> Shenyang strain 51.0 %.Immunoprotective of Guangzhou strain was significantly higher than that of other strains(P<0.01).Chickens were immunized by different strains and withdrawn to detect the level of CD4+ and CD8+ T cells.The result indicated that all strains can induce increasing quantity of CD4+ and CD8+ T cells which were very important in immunoprotective.
Keywords:chicken  E  tenella  immunoprotective
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