Ventricular rate control using a novel vagus nerve stimulating system in a dog with chronic atrial fibrillation |
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| Authors: | Dan G. Ohad DVM PhD Yitzhak Sinai DVM Asaph Zaretsky DVM Rona Shofti DVM PhD |
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| Affiliation: | aThe Koret School of Veterinary Medicine, Faculty of Agricultural, Food and Environmental Quality Sciences, PO Box 12, Rehovot 76100, Israel;bBioControl Medical, 3 Geron Street, PO Box 2713, Yehud 56100, Israel;cExperimental Surgery and Laboratory Animal Unit, Department of Biomedical Engineering, Rappaport Institute of Research in the Medical Sciences, Faculty of Medicine, Technion–Israel Institute of Technology, 1 Efron Street, Haifa 31096, Israel |
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| Abstract: | A 4-year-old, intact male Dogue de Bordeaux dog with congenital valvular pulmonic stenosis, tricuspid valve dysplasia, and chronic atrial fibrillation underwent ultrasound-guided balloon valvuloplasty in addition to pharmacological treatment. Owner compliance to prescribed pharmacotherapy proved very poor, and concerns developed regarding the ability to successfully control heart rate and symptoms using drug therapy alone. These concerns were addressed by the implantation of a novel vagal stimulation system that was programmed to prevent a ventricular rate of >145 bpm. Consequently, post-operative ventricular response rate decreased from up to 250 to 140 bpm. Successful ventricular rate control was maintained for 291 days post-operatively, following which euthanasia was elected by the owner due to persistent right-sided congestive heart failure. To the authors' knowledge, this is the first report of successful continuous rate control using a vagal stimulating system in a closed-chest, client-owned dog with chronic atrial fibrillation secondary to spontaneously occurring organic heart disease. |
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| Keywords: | Canine Dogue de Bordeaux Bordeaux dog Vagal stimulation Ultrasound-guided valvuloplasty |
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