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Critical anthelmintic trials in ponies with oxfendazole and caviphos and concomitant studies on the spontaneous elimination of small strongylids.
Authors:M L Colglazier
Abstract:The efficacy of the benzimidazole, oxfendazole, and the organophosphate, caviphos, against gastrointestinal parasites of ponies was evaluated by the critcial test method. Oxfendazole (10 mg/kg of body weight) given in single oral doses was 100% effective against adult large strongylids (Strongylus vulgaris, Strongylus edentatus, and Strongylus equinus), 99% effective against adult small strongylids, and 97% effective against 4th-stage small strongylids (genera identified in order of frequency: Cylicostephanus, Cyathostomum, Cylicocyclus, Triodontophorus, Poteriostomum, Oesophagodontus, Cylicodontophorus, Gyalocephalus, and Craterostomum). Caviphos (40 mg/kg of body weight) admixed in the grain ration (horse crunch) was 89% effective against adult large strongylids (S vulgaris and S edentatus) and 99% effective against adult small strongylids (genera identified earlier in order of frequency above), but only 35% effective against 4th-stage small strongylids. Both drugs were effective (100%) against adult and immature pinworms (Oxyuris equi) but ineffective against Habronema spp and Draschia megastoma. Oxfendazole was only 11% effective against stomach bots (Gasterophilus spp); caviphos was 73% effective against these species. During a three-day pretreatment interval, about 34% of the total population of small strongylids was lost spontaneously from the 29 ponies.
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