Analysis of complex cytogenetic alterations in three canine mammary sarcomas. |
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Authors: | B Mayr E Kramberger-Kaplan G Loupal W Schleger |
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Affiliation: | Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria. |
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Abstract: | Cells of mammary sarcomas in three dogs were analysed cytogenetically. In an osteoidsarcoma, hyperdiploidy with a range of 92 to 98 chromosomes, and several structural aberrations (for example, a derivative chromosome 1, isochromosome 13 and several bi-armed markers) were observed. Isochromosome 13 was also present in a case of an osteoidchondrosarcoma. In a case of chondro-osteosarcoma both hypodiploidy with a chromosome range of 60 to 66 and hyperdiploidy with a range of 115 to 128 and several centric fusions were observed. |
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