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The circular RNA circCPE regulates myoblast development by sponging miR-138OA
作者姓名:Wenxiu Ru  Ao Qi  Xuemei Shen  Binglin Yue  Xiaoyan Zhang  Jian Wang  Hui Cao  Hong Chen
作者单位:Key laboratory of Animal Genetics;Shaanxi Kingbull Livestock co.
基金项目:supported by the National Natural Science Foundation of China[Grant No.31772574];Major project of collaborative innovation of industry,university,research and application in Yangling Demonstration Zone(2018CXY-05).
摘    要:Background: Skeletal muscle development, a long-term and complex process, is controlled by a set of the myogenic genes. Circular RNAs(circRNAs), a class of noncoding RNA, have been shown to regulate various biological processes. Recent studies indicate circRNAs may be involved in myogenesis, but the role and regulatory mechanism of circRNAs in myogenesis is largely unknown. In the present study, circCPE was firstly found to promote the bovine myoblast proliferation and inhibit cell apoptosis and...

关 键 词:APOPTOSIS  BOVINE  CircRNA  DIFFERENTIATION  MiR-138  PROLIFERATION

The circular RNA circCPE regulates myoblast development by sponging miR-138
Wenxiu Ru,Ao Qi,Xuemei Shen,Binglin Yue,Xiaoyan Zhang,Jian Wang,Hui Cao,Hong Chen.The circular RNA circCPE regulates myoblast development by sponging miR-138[J].Journal of Animal Science and Biotechnology,2022(1):66-81.
Authors:Wenxiu Ru  Ao Qi  Xuemei Shen  Binglin Yue  Xiaoyan Zhang  Jian Wang  Hui Cao  Hong Chen
Abstract:Background:Skeletal muscle development, a long-term and complex process, is controlled by a set of the myogenic genes. Circular RNAs (circRNAs), a class of nonc...
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