家禽密切接触人群禽流感和新城疫血清学调查

为了评估家禽密切接触人群感染新城疫和禽流感病毒的风险,分别采集21份规模化养禽场和20份从事禽产品加工的屠宰场工作人员血清样品，采用微量中和试验检测人血清样品中新城疫和禽流感(H5和H9亚型)病毒抗体。结果发现，养禽场工作人员新城疫病毒抗体阳性率为33.3%,禽流感(H5和H9亚型)病毒抗体均为阴性；屠宰场工作人员新城疫病毒抗体阳性率为5%,禽流感(H5和H9亚型)病毒抗体均为阴性。结果表明新城疫病毒能够感染人,而目前国内流行的禽流感病毒感染人群的可能性较小。但是,由于禽流感病毒很容易发生变异和持续进化,有必要对家禽密切接触人群进行血清学监测。

Serological survey for newcastle disease and avian influenza of people with occupational poultry exposure

In order to assess the infected risk of newcastle disease virus(NDV) and avian influenza virus(AIV) of workers occupationally exposed to poultry, a survey was conducted among workers in large-scale poultry farms and poultry products processing factory. Serum samples of 21 poultry workers and 20 workers in poultry product processing factory were collected and tested for NDV, H5N1 and H9N2 neutralizing antibodies by microneutralization assay. All participants showed negative for H5N1 and H9N2 neutralizing antibodies. Seven poultry workers and one worker of poultry products processing factory were tested positive for NDV neutralizing antibodies. The results showed that the newcastle disease virus could infect human, and there's little possibility of AIV (H5N1 and H9N2 subtype)transmission among people with occupational poultry exposure. Despite no serological evidence of AIV infection was identified among participants, continued surveilance for AIV in humans and further seroprevalence invesitigations were needed to assess the risk of avian to human transmission, in case that AIV continued to circulate and evolve among poultry．