中兽药新制剂清瘟败毒颗粒对鸡人工感染支气管炎的防治试验

鸡传染性支气管炎是一种急性高度接触性呼吸道传染病，影响鸡的产蛋量和蛋品质。本研究以鸡传染性支气管炎病毒标准株M41人工感染21日龄700只海兰褐雏鸡，使其发病。接种病毒前后在饮水中分别添加不同剂量的清瘟败毒颗粒，以清瘟败毒散为对照治疗组，观察不同处理鸡的临床症状、发病率、病理变化和死亡率等。结果表明：饮水中添加0．z5％o清瘟败毒颗粒，对IBV标准株M41的攻毒保护作用与阳性对照组相比较差异显著（P〈0．05）；清瘟败毒颗粒低剂量治疗组与高、中剂量治疗组及清瘟败毒散治疗组之间差异显著，因水中添加0．5‰清瘟败毒颗粒，对人工感染鸡传染性支气管炎治疗作用明显，治愈率达88．00％，显著高于清瘟败毒散治疗组（P〈0．05）。

Experiment of Preventive and Curative Effect of Qingwen Baidu Granules on the Artificial Chicken Infectious Bronchitis

Chicken infectious bronchitisis is a highly acute contagious disease which infected by respiratory tract. The egg production and egg quality was affected. Seven hundred three-week-old Hy-line variety brown artificial chickens infectious bronchitis by standard M41 strain of IBV were divided into seven groups at random. Before or after inoculation, different dosages of Qingwen Baidu granules were added into drinking water to observe the clinical symptom, incidence rate, pathological alterations and fatality rate, and with Qingwen Baidu powder as positive control drug. The results showed that 0.25 ‰ Qingwen Baidu granules in water can significantly protect the chickens from IBV strains M41 attack than positive control group. Nought five permillage of Qingwen Baidu granules in drinking water can effectively cure the artificial chickens infectious bronchitis by standard M41 strain of IBV, and the curative rate is 88 .00%, signficantly higher than that of Qingwen Baidu powder treatment group and low dose treatment group or positive control group.