Morphogenesis and distribution of the endocrine pancreas in adult lampreys |
| |
Authors: | John H Youson W Mar Elliott |
| |
Institution: | (1) Department of Zoology and Scarborough Campus, University of Toronto, West Hill, Ontario, M1C 1A4, Canada |
| |
Abstract: | The endocrine pancreas of larval lampreys appears as islets of cells isolated in the submucosa and those both continuous with,
and within, the gut epithelium at the intestinal-oesophageal-bile duct junction. The islets, and occasionally follicles, are
composed of only insulin-secreting (B) cells. During metamorphosis, the bile duct either completely degenerates or its epithelium
transforms into a caudal endocrine pancreas while a cranial pancreas appears as a specialization and expansion of the larval
pancreas. Immunocytochemistry and histochemistry demonstrates that there is a wide variation in the distribution of the pancreatic
tissue in adults of lamprey species, and this variation may result from interspecific differences in morphogenetic events
at metamorphosis. Despite species variability in its distribution, the endocrine pancreatic tissue in all adult lampreys is
composed of equal numbers of B cells and somatostatin-secreting (D) cells, but there are no glucagon-secreting (A) cells.
Immunocytochemistry reveals that B and D cells of the caudal pancreas differentiate from cells of the larval bile duct during
metamorphosis of the sea lamprey,Petromyzon marinus. |
| |
Keywords: | adult lamprey endocrine pancreas morphogenesis distribution immunocytochemistry somatostatin insulin |
本文献已被 SpringerLink 等数据库收录! |
|