Persistent polyuria in two dogs following adrenocorticolysis for pituitary-dependent hyperadrenocorticism |
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| Authors: | W J Biewenga A Rijnberk J A Mol |
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| Institution: | Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands. |
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| Abstract: | In two dogs with pituitary-dependent hyperadrenocorticism, adrenocorticolysis with o.p'-DDD led to the disappearance of the signs and symptoms except for the polyuria. After a modified water-deprivation test the osmoregulation of vasopressin release was studied by hypertonic saline infusion. In both dogs the hypertonicity, thus induced, resulted in very minimal responses of the vasopressin secretion. |
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