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Anti-plasmodial activity of the extracts and two sesquiterpenes from Cyperus articulatus
Authors:Rukunga G M  Muregi F W  Omar S A  Gathirwa J W  Muthaura C N  Peter M G  Heydenreich M  Mungai G M
Affiliation:Kenya Medical Research Institute (KEMRI), PO BOX 54840, Nairobi, Kenya. grukunga@kemri.org
Abstract:Two sesquiterpenes, corymbolone and mustakone, isolated from the chloroform extract of the rhizomes of Cyperus articulatus, exhibited significant anti-plasmodial properties. Mustakone was approximately ten times more active than corymbolone against the sensitive strains of the Plasmodium falciparum.
Keywords:Cyperus articulatus   Anti-plasmodial activity   Sesquiterpenes
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