| 水泡性口炎病毒核酸疫苗对BALB/c小鼠免疫原性研究 |
| |
| 引用本文： | 周学章,高丰,李元刚,王玉炯.水泡性口炎病毒核酸疫苗对BALB/c小鼠免疫原性研究[J].中兽医医药杂志,2007,26(5):8-12. |
| |
| 作者姓名： | 周学章 高丰 李元刚 王玉炯 |
| |
| 作者单位： | 宁夏大学生命科学院教育部重点实验室 宁夏银川750021(周学章，李元刚，王玉炯)，吉林大学畜牧兽医学院 吉林大学畜牧兽医学院(高丰) |
| |
| 摘 要： | 成功构建了pIRES-G1500基因的重组核酸疫苗质粒,用核酸疫苗免疫BALB/c小鼠,测定注射质粒的小鼠细胞免疫和体液免疫指标相关参数的变化,评价核酸疫苗在体内表达效果。
|
| 关 键 词： | 水泡性口炎病毒 免疫原性 pIRES-G1500基因 |
| 文章编号： | 1000-6354（2007）05-0008-05 |
| 收稿时间： | 2007-06-16 |
| 修稿时间： | 2007-06-16 |
Immunogenecity of nucleic acid vaccine against vesicular stomastitis in BALb/c mice |
| |
| ZHU Xue-zhang, LI Yuan-gang, WANG Yu-jiong.Immunogenecity of nucleic acid vaccine against vesicular stomastitis in BALb/c mice[J].Journal of Traditional Chinese Veterinary Medicine,2007,26(5):8-12. |
| |
| Authors: | ZHU Xue-zhang LI Yuan-gang WANG Yu-jiong |
| |
| Institution: | Key lab of the Ministry of Education, College of Life Sciences, Ningxia University, Yinchuan Ningxia 750021 China |
| |
| Abstract: | pIRES-G1500,the recombinant plasmids of nucleic acid vaccine against vesicular stomastitis,was constructed by cloning G1500 genes into eukaryotic expression vector pIRESneo.Then BALb/c mices were immunized with the nucleic cid vaccine plasmids.The responses of specific cellular immunity and humoral immunity were evaluated by immunological methods.The results indicated the mice immunized with the nucleic acid vaccine could transfer immunity against vesicular stomastitis. |
| |
| Keywords: | vesicular stomatitis virus immunogenecity pIRES-G1500 gene |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
