Automated analysis of feline platelets in whole blood,including platelet count,mean platelet volume,and activation state |
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Authors: | Zelmanovic David Hetherington Edward J |
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Institution: | Bayer Diagnostics Division, 511 Benedict Ave., Tarrytown, NY 10591, USA. |
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Abstract: | A new whole-blood flow cytometric method has been developed for counting and sizing platelets in samples from cats, a species in which platelet and red blood cell sizes overlap significantly. The method is a modified version of the two-angle laser light scattering technology used by Bayer H*System hematology analyzers. The new method provided accurate platelet counts and mean platelet volumes (MPV, fl) for cats. The method also measured mean platelet component concentration (MPC, g/dl), a parameter which was shown to be sensitive to platelet activation state, and which decreased in value as activation progressed. |
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Keywords: | feline whole blood platelet counts MPV activation state |
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