|
|||||
|
|
Cytotoxic activity of lignans from Hibiscus cannabinus |
|
| Authors: | Moujir Laila Seca Ana M L Silva Artur M S López Manuel R Padilla Nayely Cavaleiro José A S Neto Carlos P |
| Institution: | Department of Microbiology and Cellular Biology, and Instituto Canario de Investigación del Cáncer, University of La Laguna, 38206 La Laguna, Tenerife, Spain. lmoujir@ull.es |
| Abstract: | The antimicrobial and cytotoxic activities of six lignans isolated from the core and bark acetone extracts of Hibiscus cannabinus have been investigated. Two compounds (2 and 3) showed strong cytotoxic activity against HeLa, Hep-2 and A-549 cell lines while compound 5 showed moderate activity on HeLa cells when they were in advanced stage of cellular division. The compounds did not exhibit antimicrobial activity. |
| Keywords: | Hibiscus cannabinus Lignans Cytotoxic activity Antimicrobial activity |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |