| 年龄对SAMP8小鼠新物体再认能力的影响 |
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| 引用本文： | 杨启纲,陈贵海. 年龄对SAMP8小鼠新物体再认能力的影响[J]. 安徽农业大学学报, 2006, 33(2): 167-169 |
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| 作者姓名： | 杨启纲 陈贵海 |
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| 作者单位： | 安徽医科大学第一附属医院神经内科,合肥,230032;安徽武警医院,合肥,230041;安徽医科大学第一附属医院神经内科,合肥,230032 |
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| 基金项目： | 安徽省自然科学基金 , 安徽省教育厅自然科学基金 |
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| 摘 要： | 探讨年龄对快速老化敏感小鼠8(SAMP8)短期再认记忆能力的影响.结果表明,与3及7月龄小鼠比较,11月龄SAMP8小鼠的新物体再认能力增强.与对照的11月龄SAMR1(快速老化抵抗小鼠1)小鼠比较,11月龄SAMP8小鼠的新物体再认能力也增强.这种记忆的增强不受性别因素的影响. 这些结果提示在衰老过程中,SAMP8小鼠的新物体再认能力增强.
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| 关 键 词： | 行为 记忆 小鼠 衰老 |
| 文章编号： | 1672-352X（2006）02-0167-03 |
| 收稿时间： | 2005-11-03 |
| 修稿时间： | 2005-11-03 |
Effects of age on ability of novel-object recognition in senescence-accelerated prone mouse 8 |
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| YANG Qi-gang,CHEN Gui-hai. Effects of age on ability of novel-object recognition in senescence-accelerated prone mouse 8[J]. Journal of Anhui Agricultural University, 2006, 33(2): 167-169 |
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| Authors: | YANG Qi-gang CHEN Gui-hai |
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| Abstract: | The effect of age on the ability of novel-object recognition in mice was explored,the results showed that the ability of novel-object recognition in eleven-month-old senescence-accelerated prone mouse 8(SAMP8) increased in comparison to the three-and seven-month-old mouse in the novel-object recognition task.Compared to the control strain,senescence-accelerated resistant mouse 1(SAMR1) at age of 11 months,the ability of mouse 8(SAMR8) in the eleven-month-old increased,too.The results suggest that during aging,the ability of novel-object recognition in SAMP8 mice may increase. |
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| Keywords: | behavior memory mouse aging |
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