肾间质纤维化的病理与螺旋CT动态增强扫描对照研究

目的通过不同程度肾间质纤维化(RIF)肾穿刺病理检查(RBP)与螺旋CT薄层动态增强扫描(SCTDCS)对照,探讨RIF病理与螺旋CT诊断指标之间的相关性。方法收集经RBP检查证实的正常及轻中重度RIF患者112例,肾活检病理组织行光镜及免疫组化检查,行肾脏SCTDCS作出影像诊断。结果中、重度RIF组肾皮/髓质厚度比、CT值及肾体积改变与对照组相比,差异均具有统计学意义(P<0.05),与轻度组比较,差异无统计学意义(P>0.05);SCTDCS诊断RIF的敏感性为70.7%,准确性为78.6%,特异性为86.7%。结论SCTDCS通过综合判断肾脏相关指标其诊断RIF的敏感性、特异性、准确性较高,可为临床诊断RIF提供影像学依据。

Control study between renal biopsy and dynamic contrast scanning of spiral CT in renal interstitial fibrosis

Objective To investigate the relationship between renal biopsy pathology (RBP) and spiral CT dynamic contrast scanning (SCTDCS) in renal interstitial fibrosis (RIF). Methods A total of 112 patients with renal diseases underwent RBP and SCTDCS; of them, there were 82 patients with RIF. Results SCTDCS findings showed that there was statistical differences in the ratio of cortex/medulla thickness, CT value, and dimension change between patients with and without RIF (P<0.05). The sensitivity, accuracy and specificity of SCTDCS were 70.7%, 78.6% and 86.7%, respectively. Conclusion SCTDCS can be helpful in the diagnosis of RIF.