Feline leukaemia virus: Half a century since its discovery |
| |
| Authors: | Brian J. Willett Margaret J. Hosie |
| |
| Affiliation: | 1. Virology Laboratory, Institute of Basic Health Sciences, Universidade Federal do Rio Grande do Sul, Rua Sarmento Leite 500, Porto Alegre, RS CEP 90150-070, Brazil;2. Centro Universitário Ritter dos Reis — UniRitter, Health Science Department, Rua Orfanotrófio, 555, Alto Teresópolis, Porto Alegre, RS CEP 90840-440, Brazil;3. Clinical Veterinary Laboratory, Veterinary Faculty, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Bairro Agronomia, Porto Alegre, RS CEP 90540-000, Brazil;4. Clinical Veterinary Hospital, Veterinary Faculty, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Bairro Agronomia, Porto Alegre, RS CEP 90540-000, Brazil;1. Miami University, 501 E High St, Oxford, OH 45056, 6249 Aspen Ave, Cincinnati, OH 45224, United States of America;2. Ethicon, Inc. 4545 Creek Rd, Cincinnati, OH 45242, United States of America |
| |
| Abstract: | In the early 1960s, Professor William (Bill) F.H. Jarrett was presented with a time–space cluster of cats with lymphoma identified by a local veterinary practitioner, Harry Pfaff, and carried out experiments to find if the condition might be caused by a virus, similar to lymphomas noted previously in poultry and mice. In 1964, the transmission of lymphoma in cats and the presence of virus-like particles that resembled ‘the virus of murine leukaemias’ in the induced tumours were reported in Nature. These seminal studies initiated research on feline leukaemia virus (FeLV) and launched the field of feline retrovirology. This review article considers the way in which some of the key early observations made by Bill Jarrett and his coworkers have developed in subsequent years and discusses progress that has been made in the field since FeLV was first discovered. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
