Giant hepatic mitochondria: production in mice fed with cuprizone |
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Authors: | K Suzuki |
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Abstract: | Giant mitochondria in hepatocytes that have the average size of nuclei can be consistently produced in the liver of weanling mice by feeding them cuprizone (bis-cyclohexanone oxaldihydrazone). The simplicity of the procedure and the consistency of the results make the feeding of cuprizone a new and useful experimental tool for the study of mitochondrial metabolism. |
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