干姜的镇静作用研究

[目的]探讨干姜的镇静作用。[方法]采用灌胃给药方式,通过对给药后与给药前进行对比,研究不同浓度干姜水煎液(1、2、3mg/ml)对小白鼠自主活动情况的影响。[结果]当干姜水煎液浓度为1 g/ml时,其对小鼠的走动时间及举前肢数在一定时间(给药后2.5 h)内都有非常明显的抑制作用;当浓度为2 g/ml时,干姜对小鼠的走动时间及举前肢数也有较为显著的影响,但抑制时间较浓度为1 g/ml时缩短;当浓度为3 g/ml时,干姜对小鼠的抑制作用不明显。[结论]干姜有一定的镇静作用,作用大小与剂量有关。

Study on Sedation of Dried Ginger

[Objective] The experiment aimed to explore sedation of dried ginger.[Method] By compared the experimental results before and after intragastric administration,the influences of decoction of dried ginger at different concentrations(1,2,3 mg/ml) on locomotor activities of white mice.[Result]When the decoction of dried ginger was 1 g/ml,the time of free movements and the number of raising forelimbs of mice were obviously detained(2.5 h after intragastric administration).When the decoction of dried ginger was 2 g/ml,the time of free movements and the number of raising forelimbs of mice were obviously influenced however the inhibition time is short than that of 1 g/ml.When the decoction of dried ginger was 3 g/ml,the inhibition is not obvious.[Conclusion] Dried ginger had some sedation effect which was related to its dosage.