| 不同物种MHC-DQA1基因部分序列的生物信息分析 |
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| 引用本文： | 郭秀丽,代红星,李祥龙,周荣艳,王立泽. 不同物种MHC-DQA1基因部分序列的生物信息分析[J]. 中国畜牧兽医, 2007, 34(1): 65-67 |
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| 作者姓名： | 郭秀丽 代红星 李祥龙 周荣艳 王立泽 |
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| 作者单位： | 河北农业大学动物科技学院，保定 071001 |
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| 摘 要： | 作者应用比较基因组学和生物信息学方法比较了绵羊、牛、鹿和狗MHC-DQA1基因部分序列，并对该基因的遗传多样性及分子系统发育进行了分析。结果表明，38个基因序列检测到107个多态位点，共生成38个单倍型。物种间及物种内MHC DQA1存在较丰富的遗传多样性。
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| 关 键 词： | 物种 MHC-DQA1基因 变异 |
| 文章编号： | 1671-7236（2007）01-0065-03 |
| 修稿时间： | 2006-06-15 |
Bioinformatics Analysis of Part of MHC-DQA1 Gene in Different Species |
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| GUO Xiu-li,DAI Hong-xing,LI Xiang-long,ZHOU Rong-yan,WANG Li-ze. Bioinformatics Analysis of Part of MHC-DQA1 Gene in Different Species[J]. China Animal Husbandry & Veterinary Medicine, 2007, 34(1): 65-67 |
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| Authors: | GUO Xiu-li DAI Hong-xing LI Xiang-long ZHOU Rong-yan WANG Li-ze |
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| Affiliation: | College of Animal Science and Technology, Agricultural University of Hebei, Baoding 071001, China |
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| Abstract: | In this study,part of the MHC-DQA1 gene sequences of ovis aries,bos taurus,cervus nippon and canis familiaris were analyzed using the method of comparative genomics and bioinformatics.The genetic diversity and molecular phylogeny were analyzed.The results showed that a total of 107 polymorphic sites were detected from 38 sequences,from which 38 hapolotypes were sorted.More nucleotide diversity and amino acid diversity of MHC-DQA1 gene existed within and among species. |
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| Keywords: | species MHC-DQA1 gene variation |
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