Thrombocytopathia and Light-Chain Proteinuria in a Dog Naturally Infected With Ehrlichia canis |
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Authors: | Frederic Varela Xavier Font Josep E Valladares Jordi Alberola |
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Institution: | Centre Mèdic Veterinari de Barcelona, Balmes 81, 08008 Barcelona;Divisióde Farmacologia, Facultal de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Spam |
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Abstract: | A 6–year-old dog was presented for evaluation of recurrent epistaxis. Platelet counts, biochemical tests, and coagulation tests were within the normal range, but a mucosal bleeding time was prolonged; there was hyperproteinemia and a monoclonal gammopathy. Heterogeneity of light chains appeared in urine, however, thus suggesting that the gammopathy was polyclonal. Platelet aggregation tests showed decreased responsiveness to collagen. An Ehrlichia canis indirect fluorescent-antibody titer was positive (1:40). Treatment with tetracycline, melphalan, and prednisone resulted in a rapid clinical improvement that persisted for at least 3 years. |
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